Gene-Edited Pig Kidney Transplanted Successfully into Human


Aug 21, 2023

Gene-Edited Pig Kidney Transplanted Successfully into Human

Groundbreaking Xenotransplantation: Genetically Modified Pig Kidney Successfully Transplanted into Human

With an ever-growing demand for donated organs and a chronic shortage of available human organs for transplantation, scientists and medical researchers have been looking for alternative ways to address this dire situation. One promising area of research that is making headlines is xenotransplantation - the transplantation of non-human organs into human recipients. In a groundbreaking study, doctors in New York City have successfully transplanted a genetically modified pig kidney into a brain-dead human patient. This landmark achievement holds immense potential for the future of organ transplantation.

What is Xenotransplantation?

Xenotransplantation involves the transplantation of organs, tissues, or cells from one species to another. Historically, the concept of transplanting animal organs into humans has been explored, but the practice has faced significant challenges due to the risk of organ rejection and the potential transmission of animal-borne diseases. The advent of gene-editing technology has renewed interest in xenotransplantation, as it allows scientists to modify the organs of donor animals to make them more compatible with the human immune system.

The Breakthrough Transplant

In the recent medical breakthrough, doctors transplanted a genetically modified pig kidney into a brain-dead human recipient. The pig kidney had been genetically edited to reduce the risk of organ rejection, which is a major challenge in transplantation. Remarkably, the kidney functioned for more than a month without the body rejecting it. The pig kidney effectively took over the essential tasks that a human kidney performs, showcasing the potential of xenotransplantation to address the shortage of organs for transplantation.

Implications for the Future

There are over 100,000 Americans currently waiting for an organ transplant, with many of them in need of a kidney. Unfortunately, only about a third of these individuals will receive a transplant each year, and 17 people die each day while waiting for a transplant. The successful transplantation of a pig kidney into a human recipient brings hope to these patients and their families.

The use of pig kidneys for transplantation could potentially alleviate the severe shortage of organs available for transplantation. The success of this trial opens the door to future clinical trials involving living patients and could revolutionize the field of organ transplantation.

Ethical Considerations

While the prospect of using animal organs for transplantation is exciting, it is essential to consider the ethical implications of xenotransplantation. These include the treatment of animals used for organ donation, the long-term effects of using animal organs in humans, and the potential risks of transmitting animal-borne diseases to human recipients.


This is the story from ABC News.

The successful transplantation of a genetically modified pig kidney into a human recipient is a significant milestone in the field of organ transplantation. This achievement brings hope to the thousands of individuals waiting for a life-saving transplant and opens up new possibilities for addressing the shortage of organs. However, as with any medical advancement, it is essential to carefully consider the ethical, scientific, and medical implications of xenotransplantation before it becomes a standard practice. The potential to save lives through xenotransplantation is enormous, and ongoing research and responsible discussion will shape the future of this promising field.

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About the Author

Rich Foreman brings over 30 years of technology leadership to his role of CEO and Co-Founder of KidneySoft.  As founding CTO, Rich led the team that developed the CordicoShield / CordicoFire Wellness App. Cordico was honored with the Sacramento Innovation Award in 2021. After achieving a 7 digit ARR, Cordico was acquired by Lexipol in 2020. Rich has a BS in Industrial Engineering from the University of Washington, an MPA from Troy State University and was an officer in the U.S. Navy. Rich co-authored his book, "Tap into the Mobile Economy." Rich's blog was listed in Top 20 Marketing Mobile Blogs of 2014. He has been featured on KCRA3, NEWS10, 1170 Tech AM PowerDrive, Business Radio Money 105.5, SiliconIndia, the Sacramento Business Journal, and the Sacramento Bee. Rich is also the Founding Director of the Sacramento Chapter of Startup Grind and served a term as Utility Commissioner for the City of Folsom. Rich is a regular contributor to and StartupSac. Rich was the Co-founder of Apptology which was named Small Business of the Year in 2014 by the Sacramento Asian Pacific Chamber. He was also the Founding Chief Technology Officer at Cordico. Cordico was acquired by Lexipol in 2020.  Rich also served 4 years as a Naval Officer in the Civil Engineer Corps.

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