New Study will test Major Kidney Disease Breakthrough


Dec 20, 2023

New Study will test Major Kidney Disease Breakthrough

A Breakthrough in Kidney Disease Management

In the heart of Spokane, a revolution in kidney disease treatment is unfolding, led by Dr. Katherine Tuttle and her dedicated team at Providence Inland Northwest Health. As an esteemed researcher in this field, Dr. Tuttle's recent discovery is being hailed as a breakthrough, potentially transforming the lives of millions afflicted with this chronic condition.

The Promising New Treatment

This new treatment, set to undergo a monumental 11,000-person study by the University of Oxford, stands as one of the largest kidney disease trials ever. The drugs, deemed “astonishingly effective” by Oxford’s Professor Will Herrington, could signify a substantial leap forward in kidney care.

The Current State of Kidney Disease Treatment

Kidney disease, often a silent ailment, escalates to critical stages without early symptoms. Current treatments, primarily ACE inhibitors, offer limited effectiveness, barely impacting the vast population suffering from this disease. Despite their moderate success, these drugs are under prescribed due to widespread underdiagnosis, as highlighted by Tuttle's work with the Cure CKD registry.

A Shift in Treatment Paradigm

About five years ago, the treatment landscape shifted with the introduction of SGL2 inhibitors, initially designed for diabetes prevention. These inhibitors, when used alongside ACE inhibitors, demonstrated a significant reduction in kidney failure risk. Yet, their adoption in clinical practice remains minimal.

Tuttle's Discovery: A Game Changer

Dr. Tuttle's latest study introduces an innovative combination of existing drugs with Aldosterone Synthase Inhibitors (ASI). This trio of medications has shown a remarkable increase in efficacy, addressing the long-term limitations of ACE inhibitors and SGL2s. The initial trial in Spokane has already shown promising results, with a significant reduction in kidney damage among participants.

The Path Ahead

As Dr. Tuttle prepares for the global trial with the University of Oxford, the excitement in the medical community is palpable. The potential impact of this treatment could be transformative, reducing the number of patients progressing to kidney failure and requiring dialysis or transplantation.

A Cautionary Note

Despite the optimism, there are concerns about the broader adoption of this treatment, even if the upcoming trials are successful. The healthcare system faces the challenge of ensuring these therapies reach the patients who need them most.

Final Thoughts

Dr. Katherine Tuttle's pioneering research is not just a milestone in kidney disease treatment; it's a beacon of hope for millions. As we stand on the cusp of what could be one of medicine's most significant breakthroughs, the future looks brighter for those battling kidney disease. With continued research and a commitment to patient care, we are moving closer to a world where kidney disease is no longer a life sentence, but a manageable condition.

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‘On par with the biggest breakthroughs in medicine’: Spokane doctor discovers new kidney disease treatment. An 11,000-person study will start in 2024

About the Author

Rich Foreman brings over 30 years of technology leadership to his role of CEO and Co-Founder of KidneySoft.  As founding CTO, Rich led the team that developed the CordicoShield / CordicoFire Wellness App. Cordico was honored with the Sacramento Innovation Award in 2021. After achieving a 7 digit ARR, Cordico was acquired by Lexipol in 2020. Rich has a BS in Industrial Engineering from the University of Washington, an MPA from Troy State University and was an officer in the U.S. Navy. Rich co-authored his book, "Tap into the Mobile Economy." Rich's blog was listed in Top 20 Marketing Mobile Blogs of 2014. He has been featured on KCRA3, NEWS10, 1170 Tech AM PowerDrive, Business Radio Money 105.5, SiliconIndia, the Sacramento Business Journal, and the Sacramento Bee. Rich is also the Founding Director of the Sacramento Chapter of Startup Grind and served a term as Utility Commissioner for the City of Folsom. Rich is a regular contributor to and StartupSac. Rich was the Co-founder of Apptology which was named Small Business of the Year in 2014 by the Sacramento Asian Pacific Chamber. He was also the Founding Chief Technology Officer at Cordico. Cordico was acquired by Lexipol in 2020.  Rich also served 4 years as a Naval Officer in the Civil Engineer Corps.

Patient Education Disclaimer

This material is for informational purposes only. It does not replace the advice or counsel of a doctor or health care professional. KidneyLuv makes every effort to provide information that is accurate and timely, but makes no guarantee in this regard. You should consult with, and rely only on the advice of, your physician or health care professional.

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