Itchy Skin: A Sign of Kidney Disease

If you're experiencing itchy skin, it might be a sign of kidney disease. Kidney disease is a serious health issue that affects millions of people in the United States. However, many people don't know they have it because early stages of kidney disease don't typically cause symptoms. In this article, we'll discuss the link between itchy skin and kidney disease, including its causes, symptoms, and treatments.

What is Chronic Kidney Disease-Associated Pruritus?

Kidney disease can cause itchy skin or pruritus, which is referred to as chronic kidney disease-associated pruritus (CKD-aP) by healthcare professionals. CKD-aP can lead to a rash, dry skin, or skin lesions due to scratching.

What Causes CKD-aP?

The exact cause of CKD-aP is not clear, but theories suggest that it may involve a lack of balance in signals sent to opioid receptors in nerve cells, immune system response, high parathyroid hormone levels, high combined levels of calcium and phosphorus in the blood, or insufficient dialysis that doesn't properly remove toxins and wastes.

What Are the Symptoms of CKD-aP?

Itchy skin symptoms can last for months to years and affect different areas of the body. Some people experience itchiness on their entire body, while others only experience it in certain parts of their body. Itchy skin due to kidney disease often worsens at night, improves with activity, and worsens due to heat, stress, or other factors. People with CKD-aP may also experience reduced self-esteem, changes in mood, depression, and worsening sleep.

How is CKD-aP Diagnosed?

CKD-aP is often not diagnosed because symptoms can differ from person to person. Healthcare professionals may confirm the diagnosis through a skin exam or a review of dialysis numbers or by trying different topical treatments.

What Are the Treatment Options for CKD-aP?

Treatment may include both systemic medications, which work throughout the body, and topical products, which a person can apply directly to the affected area. Healthcare professionals may also recommend antihistamines, medication for nerve pain, ultraviolet B phototherapy, or difelikefalin for people on dialysis. Experimental treatments include the use of omega-3 and omega-6 fatty acids.

Conclusion

Itchy skin can be a sign of kidney disease, and it's essential to report any symptoms to a healthcare professional to receive a diagnosis and begin treatment. Treatment options for CKD-aP include both systemic medications and topical products, and healthcare professionals may also recommend antihistamines or medication for nerve pain. By understanding the link between itchy skin and kidney disease, we can take steps to protect our health and well-being.

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Related Articles

‍What Do Your Kidneys Do?‍

What is Chronic Kidney Disease (CKD)?

References‍

What to know about itchy skin and rashes with kidney disease

Chronic Kidney Disease – Associated Pruritus (Itchy Skin)

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‍About the Author

Rich Foreman brings over 30 years of technology leadership to his role of CEO and Co-Founder of KidneySoft.  As founding CTO, Rich led the team that developed the CordicoShield / CordicoFire Wellness App. Cordico was honored with the Sacramento Innovation Award in 2021. After achieving a 7 digit ARR, Cordico was acquired by Lexipol in 2020. Rich has a BS in Industrial Engineering from the University of Washington, an MPA from Troy State University and was an officer in the U.S. Navy. Rich co-authored his book, "Tap into the Mobile Economy." Rich's blog was listed in Top 20 Marketing Mobile Blogs of 2014. He has been featured on KCRA3, NEWS10, 1170 Tech AM PowerDrive, Business Radio Money 105.5, SiliconIndia, the Sacramento Business Journal, and the Sacramento Bee. Rich is also the Founding Director of the Sacramento Chapter of Startup Grind and served a term as Utility Commissioner for the City of Folsom. Rich is a regular contributor to TechWire.net and StartupSac. Rich was the Co-founder of Apptology which was named Small Business of the Year in 2014 by the Sacramento Asian Pacific Chamber. He was also the Founding Chief Technology Officer at Cordico. Cordico was acquired by Lexipol in 2020.  Rich also served 4 years as a Naval Officer in the Civil Engineer Corps.

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Patient Education Disclaimer

This material is for informational purposes only. It does not replace the advice or counsel of a doctor or health care professional. KidneyLuv makes every effort to provide information that is accurate and timely, but makes no guarantee in this regard. You should consult with, and rely only on the advice of, your physician or health care professional.